CTICasesLaryngeal papillomatosis with malignant transformation
Imaging findings
Chest CT shows nodular thickening and papillomas along the trachea, along with multiple cavitating and solid parenchymal nodules of varying sizes in both lungs, one of which demonstrated rapid growth into a large consolidative mass. Histopathology confirmed squamous cell carcinoma.
Key takeaways
Respiratory/tracheobronchial papillomatosis is a rare HPV-related disease. Although benign, it can undergo malignant transformation to squamous cell carcinoma, typically presenting as rapidly growing, solid, or cavitating parenchymal masses and nodules.
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