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Metastatic Osteosarcoma with Calcification

Imaging findings

Chest radiograph and CT show a large, heavily calcified/ossified pleural-based mass in the right hemithorax associated with a moderate pleural effusion. The patient had a history of primary bone osteosarcoma.

Key takeaways

Osteosarcoma has a high propensity for hematogenous dissemination to the lungs and pleura. These metastatic lesions typically retain the bone-forming capacity of the primary tumor, presenting as dense, calcified, or ossified pulmonary masses that can simulate benign calcifying infections.

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