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Esophageal Myxoid Leiomyosarcoma

Esophageal Myxoid Leiomyosarcoma▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Chest radiograph shows double contours along the right heart border, a split carina, and retrocardiac bulges on the lateral view, simulating cardiac chamber enlargement. Chest CT demonstrates a massive, elongated, low-attenuation (25 HU) retrocardiac mass. The mass severely flattens the posterior aspect of the left ventricle and splays the esophageal lumen without causing mechanical destruction of the esophageal wall.

Key takeaways

Myxoid leiomyosarcoma is a rare, low-grade malignant smooth muscle tumor of the esophagus. Its high myxoid/gelatinous content results in characteristic low CT attenuation (typically 20–30 HU), which can easily lead to a misdiagnosis of a benign duplication cyst, although the tumor is surprisingly firm and slimy rather than cystic upon resection.

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