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Aspergillus calidoustus Pneumonia

Imaging findings

Frontal chest radiograph and CT demonstrate a large, well-circumscribed fungal-like pulmonary nodule/mass in the right upper lobe, surrounded by baseline diffuse, bilateral ground-glass opacities.

Key takeaways

Aspergillus calidoustus (formerly Aspergillus ustus) is a rare opportunistic pathogen in immunocompromised hosts, particularly those receiving immunosuppressive therapies like TNF-alpha inhibitors. Unlike other Aspergillus species, it is often resistant to conventional azole antifungal agents, requiring accurate identification and targeted therapy.

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