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Libman-Sacks Endocarditis

Imaging findings

CT angiogram and echocardiography show multiple small, irregular, non-mobile filling defects (vegetations) on the ventricular and atrial surfaces of the aortic valve leaflets in a patient with systemic lupus erythematosus (SLE).

Key takeaways

Libman-Sacks endocarditis is a sterile, non-infectious verrucous endocarditis associated with SLE and antiphospholipid syndrome. It typically affects the mitral and aortic valves, characteristically on the undersurface of the leaflets, and is treated with systemic immunosuppression/anticoagulation.

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