CTICasesThymic Squamous Cell Carcinoma
Imaging findings
Chest CT and MRI demonstrate an anterior mediastinal mass invading local tissue, which is radiographically indistinguishable from an aggressive thymoma. Pathological resection and immunohistochemistry show a p40 and CD5 positive squamous cell carcinoma.
Key takeaways
Thymic carcinoma (most commonly squamous cell carcinoma) is a highly aggressive malignant epithelial tumor of the thymus. It is differentiated from thymoma by cytological atypia and immunohistochemical markers such as CD5 and p40 positivity.
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