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Invasive Thymoma with SVC Invasion

Imaging findings

Contrast-enhanced chest CT and FDG-PET demonstrate an invasive anterior mediastinal mass (thymoma) extending directly into the left brachiocephalic vein and superior vena cava. Prominent systemic venous collateral channels are visible in the chest wall, including direct collateral drainage into the left superior pulmonary vein and left atrium.

Key takeaways

Thymomas are typically slow-growing tumors but can occasionally exhibit highly invasive behavior, including direct vascular invasion of the major mediastinal veins. In cases of severe superior vena cava obstruction, unusual systemic-to-pulmonary collateral pathways can develop, sometimes dumping directly into the left atrium.

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