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Cryptogenic Organizing Pneumonia

Imaging findings

High-resolution CT shows multifocal, geographic, subpleural ground-glass and consolidative opacities, with classic findings including the reverse halo sign. Follow-up imaging shows marked improvement after corticosteroid therapy, with subsequent recurrence in different lung regions upon steroid taper.

Key takeaways

Cryptogenic organizing pneumonia typically presents with multifocal consolidations, ground-glass opacities, and characteristic signs like the reverse halo or atoll sign. COP is highly responsive to corticosteroids, but a classic migratory pattern or clinical relapse can occur during steroid tapering, requiring a prolonged and gradual treatment course.

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