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Eosinophilic granulomatosis with polyangiitis

Imaging findings

Chest radiographs and CT scan show rapid progression over two months from normal findings to patchy, non-segmental, upper lung-predominant consolidations and pleural effusions. Bronchoalveolar lavage demonstrated pulmonary hemorrhage with 30% eosinophils, and blood work showed peripheral eosinophilia.

Key takeaways

Eosinophilic granulomatosis with polyangiitis is a systemic small-to-medium vessel vasculitis characteristically associated with asthma and peripheral eosinophilia. Radiographically, it often manifests as transient or progressive patchy consolidations resembling eosinophilic pneumonia or alveolar hemorrhage, and a significant minority of patients can be ANCA-negative.

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