CTICasesExtrapleural Fat Hyperplasia in Chronic Diffuse Pleural Disease
Imaging findings
In a patient with chronic diffuse unilateral pleural thickening, CT shows marked hyperplasia/hypertrophy of the extrapleural fat layer along the affected hemithorax, more pronounced than on a prior comparison study performed before the pleural thickening developed.
Key takeaways
Extrapleural fat hyperplasia is a recognized reactive response to chronic pleural thickening and volume loss -- analogous to the fat proliferation seen adjacent to severe pulmonary fibrosis -- and should be recognized as a benign accompaniment of chronic pleural disease rather than a separate process.
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