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Tracheal Involvement of Granulomatosis with Polyangiitis (GPA)

Imaging findings

A young patient with known granulomatosis with polyangiitis (GPA) and shortness of breath has imaging showing marked irregularity, narrowing, and soft-tissue thickening of the trachea just below the level of the vocal cords/hyoid, which could be mistaken for post-intubation injury but corresponds to biopsy-proven tracheal ulceration.

Key takeaways

Subglottic and tracheal wall irregularity with narrowing in a patient with a GPA history represents tracheobronchial GPA rather than a post-intubation stricture, and can be confirmed by direct bronchoscopic visualization of ulcerated tracheal mucosa.

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