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Cytomegalovirus Pneumonitis

Imaging findings

CT in a heart transplant recipient shows emphysema and diffuse, fuzzy, randomly distributed tiny pulmonary nodules, along with focal consolidation and mucus plugging in the left lower lobe. The patient had high CMV viremia and aspergillus in the BAL.

Key takeaways

Cytomegalovirus (CMV) is a common viral pathogen in solid organ transplant recipients, typically presenting between 1 and 6 months post-transplant. Pulmonary manifestations include diffuse, ill-defined centrilobular or random tiny nodules, ground-glass opacities, and consolidations. It often co-exists with other opportunistic infections like Aspergillus.

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