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Systemic AL Amyloidosis

Imaging findings

Chest CT shows progressive thickening of the interlobular septa in a patient who underwent heart transplantation for cardiac amyloidosis. Cryobiopsy confirmed pulmonary parenchymal amyloid deposition.

Key takeaways

Pulmonary involvement in AL amyloidosis can present as progressive interlobular septal thickening mimicking pulmonary edema. Heart transplantation may be performed for cardiac amyloidosis, but systemic disease can still progress in the lungs.

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