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Tracheobronchial and Parenchymal Amyloidosis

Imaging findings

Chest CT shows lumpy-bumpy wall thickening and spotty calcification of the segment and subsegmental bronchi, sparing the trachea. Multiple thin-walled perivascular pulmonary cysts, some with fluid levels, are present in the lower lobes.

Key takeaways

Amyloidosis can involve both the tracheobronchial tree (spared trachea in this variant) and the lung parenchyma (manifesting as perivascular cysts and nodules). This must be distinguished from lymphoid interstitial pneumonia (LIP).

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