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Tracheobronchial Amyloidosis

Imaging findings

Chest CT shows circumferential thickening and faint calcification of the bronchial walls, sparing the trachea. Bronchoscopy shows submucosal cobblestone-like nodules. Biopsy confirmed Congo red-positive amyloid deposits with cartilaginous metaplasia. Lower lobe cystic changes and bronchiectasis are also present.

Key takeaways

Tracheobronchial amyloidosis can present with bronchial wall thickening, calcification, and mucosal cobblestoning. It can be associated with distal airway obstruction, bronchiectasis, and localized cystic changes due to protein deposition.

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