CTICasesAnti-Synthetase Syndrome
Imaging findings
Serial chest CTs from 2003 to 2017 show progressive lower lobe-predominant cystic lung disease and ground-glass opacities, without significant traction bronchiectasis. These findings represent a form of non-uip fibrosing interstitial lung disease associated with autoimmune disease.
Key takeaways
Anti-synthetase syndrome can present with atypical cystic interstitial lung disease and ground-glass changes, mimicking other connective tissue diseases or uip. It is associated with specific non-Jo-1 antibodies and clinical Myositis.
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