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Mediastinal Fat Infarction

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Imaging findings

A CT scan reveals abnormal opacity involving the mediastinal fat adjacent to the right atrium, with an internal attenuating component. Subsequent follow-up scans over several months demonstrate progressive resolution of this finding. The patient presented with substernal chest pain radiating to the right.

Key takeaways

Spontaneous necrosis of mediastinal fat (mediastinal fat infarction) is a self-limiting inflammatory condition that typically presents with chest pain. It has a characteristic appearance on CT and resolves spontaneously over time, which helps differentiate it from more serious pathologies. While often seen on the left, it can also occur on the right side.

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