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Non-Functioning Mediastinal Paraganglioma with Pulmonary Embolism

Non-Functioning Mediastinal Paraganglioma with Pulmonary Embolism▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Chest radiograph shows two subtle abnormalities: an extra bulge in the AP window (mediastinal mass) and an opacity in the right lower lobe partially obscuring the hemidiaphragm (Hampton's hump, indicative of infarct). CT reveals a hypervascular anterior mediastinal mass with numerous vessels, consistent with a paraganglioma, and acute pulmonary emboli in central and peripheral pulmonary arteries, with an associated peripheral infarct in the right lower lobe.

Key takeaways

Mediastinal paragangliomas are hypervascular neuroendocrine tumors that can present as an anterior mediastinal mass. It is important to avoid satisfaction of search, as multiple unrelated acute pathologies, such as a pulmonary embolism with infarct, can coexist with an incidental or unrelated mediastinal mass.

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