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Pulmonary Amyloidosis with Hemorrhage into Cysts

Pulmonary Amyloidosis with Hemorrhage into Cysts▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

A lady with a history of Sjögren syndrome presented with pulmonary amyloidosis. Initial CT (2009) showed numerous pulmonary cysts, some with vessels running through them, and partially calcified nodules. Five years later (2014), she presented with hemoptysis, and one of the right middle lobe cysts was filled with intermediate attenuation fluid, consistent with blood. A follow-up study showed resolution of the blood and shrinkage of the cyst into a smaller nodule. Tracheal amyloid deposition was also noted.

Key takeaways

This interesting case demonstrates typical pulmonary amyloidosis with nodular, cystic, and tracheal involvement in a patient with Sjögren syndrome. A unique aspect was the acute presentation of hemoptysis due to hemorrhage into a pulmonary cyst, which subsequently resolved and scarred down. This highlights a rare complication of pulmonary amyloidosis.

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