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Pulmonary Amyloidosis Secondary to Sjögren's Syndrome

Pulmonary Amyloidosis Secondary to Sjögren's Syndrome▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

CT of a 50-year-old female with Sjögren's syndrome shows multiple, progressive, lobulated, solid pulmonary nodules containing punctate calcification, scattered across several lobes. Biopsy confirmed amyloid deposition.

Key takeaways

Pulmonary amyloidosis is a known manifestation of Sjögren's syndrome that typically presents as multiple calcified or non-calcified nodules. It is part of the lymphoproliferative spectrum of Sjögren's-associated lung disease and can mimic lymphoma or lymphoid interstitial pneumonia.

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