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Lymphangitic carcinomatosis

Imaging findings

Chest CT and PET/CT show diffuse, nodular interlobular septal thickening with beaded appearance (lymphatic pearls), peribronchovascular bundle thickening, and intense FDG avidity in both lungs, representing lymphangitic spread from colorectal carcinoma.

Key takeaways

Lymphangitic carcinomatosis is a pattern of tumor metastasis along pulmonary lymphatics. It presents as nodular or beaded septal thickening (lymphatic pearls) and must be differentiated from pulmonary edema.

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