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Fatal pulmonary Mucormycosis post-heart transplant

Imaging findings

CT scan in a patient one month post-heart transplant shows bilateral ground-glass opacities that rapidly progressed to a large left lower lobe consolidation with liquefaction necrosis and a 'bird's nest' pattern of internal lucencies.

Key takeaways

Mucormycosis is a rapidly progressive, angioinvasive fungal infection in severely immunocompromised hosts. The 'bird's nest' sign (internal network of overlapping soft tissue strands within a cavity) represents liquefaction necrosis and carries a high mortality.

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