CTICasesFungal Infection with Bird's Nest Sign
Imaging findings
CT shows a large, rapidly growing cavitating pulmonary mass with a classic 'bird's nest' sign of internal mesh-like lines in a neutropenic patient. The patient was treated empirically with posaconazole for presumptive mucormycosis.
Key takeaways
In invasive pulmonary fungal infections (especially mucormycosis), early empiric treatment with active agents like posaconazole or amphotericin is often started based on characteristic CT findings (such as the bird's nest sign) before culture confirmation is achieved.
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