CTICasesThymoma with Paraneoplastic Pure Red Cell Aplasia
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Imaging findings
Subtle anterior mediastinal mass on PA chest radiograph, more obvious on the lateral view. On CT, it's a uniformly enhancing soft tissue mass in the thymic region.
Key takeaways
Thymoma can be associated with paraneoplastic syndromes, such as pure red cell aplasia (less common than myasthenia gravis, but occurring in about 5% of cases). This can lead to diagnostic delays if the thymic mass is initially overlooked, emphasizing the value of the lateral chest radiograph for detecting subtle anterior mediastinal lesions.
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