CTICasesMalignant Solitary Fibrous Tumor of the Mediastinum
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Imaging findings
Chest radiograph demonstrates a large anterior mediastinal mass. CT scan reveals a very large, heterogeneous mass with faint calcification in the left anterior mediastinum, extending to the left cardiophrenic angle and compressing adjacent lung. Pathology confirmed a malignant solitary fibrous tumor, staining for CD34.
Key takeaways
Solitary fibrous tumors, while more common in the pleural space, can occur in the mediastinum. Although radiographically they may mimic thymic lesions, their distinct pathological features, including CD34 staining, confirm the diagnosis. Malignancy is based on cellularity and atypia.
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