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Allergic Bronchopulmonary Aspergillosis

Imaging findings

CT chest shows central bronchiectasis with a large, branching, hyperdense tubular opacity (bronchial impaction) in the right upper lobe demonstrating high attenuation, with associated distal lung volume loss and mild FDG-avidity on PET-CT.

Key takeaways

Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitivity reaction to Aspergillus in patients with asthma or cystic fibrosis. The hallmark CT finding is central bronchiectasis containing high-attenuation mucus plugs. The hyperdensity is caused by the accumulation of calcium, iron, and manganese salts by the fungus.

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