CTICasesSternal and Vertebral Bone-in-Bone Appearance Secondary to Pediatric Cancer Treatment
Imaging findings
Chest radiograph and CT sagittal reformatted images demonstrate a striking bone-in-bone pattern in the vertebral bodies and sternum, characterized by a distinct inner bone margin nested within the outer cortex of the bone. Pectus carinatum is also present.
Key takeaways
A bone-in-bone appearance of the vertebrae and sternum is a classic sign of historical growth arrest. This pattern is commonly seen in patients who underwent intensive chemotherapy, radiation, or bone marrow transplantation during childhood. When normal bone growth is severely arrested and subsequently resumes, the newly formed bone surrounds the older, arrested bone, creating a nested appearance.
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