CTICasesPulmonary Alveolar Proteinosis
Imaging findings
Chest CT demonstrates a classic, widespread "crazy-paving" pattern characterized by geographic ground-glass opacity with superimposed smooth interlobular and intralobular septal thickening, showing sharp margination against spared lobules.
Key takeaways
Pulmonary alveolar proteinosis is a rare disease characterized by the accumulation of surfactant-like phospholipid-protein material within the alveoli. The classic treatment remains whole-lung lavage, which can result in near-complete clearance of the characteristic crazy-paving pattern on follow-up imaging.
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