CTICasesGastrointestinal Duodenal Amyloidosis with Concurrent Pulmonary Nodular Amyloidosis
Imaging findings
Chest CT shows multiple well-defined, bilateral, randomly distributed pulmonary nodules of varying sizes, some of which demonstrate faint internal calcification. The patient has a biopsy-confirmed diagnosis of AL amyloidosis of the duodenum.
Key takeaways
Nodular pulmonary amyloidosis is characterized by single or multiple slowly growing amyloid deposits in the lung parenchyma. While often isolated and clinically silent, nodular pulmonary amyloidosis can occur concurrently with systemic amyloidosis, such as gastrointestinal tract involvement. The presence of calcification or ossification within the nodules is a common and characteristic finding.
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