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Intralobular Gradient of Pulmonary Edema

Imaging findings

CT chest shows cardiomegaly and patchy ground-glass opacities in both lower lobes. High-resolution views demonstrate dependent layering of edema fluid within individual secondary pulmonary lobules, creating an intralobular fluid gradient.

Key takeaways

Pulmonary edema is caused by elevated hydrostatic pressures (stress failure of capillary membranes). In addition to macroscopic gravitational layering, fluid stasis can occur at the microscopic level within individual secondary pulmonary lobules, presenting as a dependent intralobular fluid gradient on CT.

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