CTICasesRecurrent Squamous Cell Carcinoma Traversing the Diaphragm
Imaging findings
Contrast-enhanced chest and abdomen CT demonstrates a large, aggressive soft-tissue mass centered at the lung base that directly traverses the diaphragm into the adjacent liver parenchyma, mimicking a hepatic abscess. Biopsy of the liver mass confirmed recurrent squamous cell carcinoma.
Key takeaways
Recurrent lung cancer can occasionally present in atypical anatomical patterns. Squamous cell carcinoma of the lung can directly invade the diaphragm and extend into the liver, mimicking a primary hepatic lesion or an infectious subphrenic/hepatic abscess. This demonstrates the clinical importance of biopsy to differentiate recurrent malignancy from infectious processes in patients with a history of lung resection.
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