CTICasesDiffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia
Imaging findings
Chest CT demonstrates innumerable small, well-defined pulmonary nodules scattered throughout both lungs, accompanied by a geographic mosaic perfusion pattern. Expiratory imaging confirms that the low-attenuation areas represent air trapping, consistent with diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH).
Key takeaways
DIPNECH is a rare preneoplastic pulmonary condition characterized by neuroendocrine cell proliferation, tumorlets, and carcinoids. The hallmark imaging features are multiple small nodules combined with mosaic perfusion and air trapping due to constrictive bronchiolitis, often showing stability over many years.
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