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Idiopathic Acute Eosinophilic Pneumonia

Imaging findings

A patient develops rapidly progressive, patchy, peripherally and basally predominant consolidation on serial radiographs and CT over about a week, with an elevated white count driven partly by peripheral eosinophilia; bronchoalveolar lavage shows a markedly elevated eosinophil percentage without evidence of vasculitis.

Key takeaways

Rapidly progressive patchy consolidation with peripheral and lavage eosinophilia, without evidence of vasculitis, represents idiopathic acute eosinophilic pneumonia -- a condition that can mimic severe infection clinically but characteristically responds dramatically to corticosteroids within hours; new or binge smoking has been reported as an associated trigger in some case series.

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