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E-cigarette or Vaping Product Use-Associated Lung Injury presenting as Acute Eosinophilic Pneumonia

Imaging findings

Chest CT in a young postpartum patient presenting with acute respiratory failure shows diffuse septal thickening, patchy ground-glass opacity with a lobular distribution, and small, bilateral pleural effusions, mimicking cardiogenic pulmonary edema. Bronchoalveolar lavage fluid reveals a marked increase in eosinophils, which rapidly cleared after starting high-dose corticosteroids.

Key takeaways

Vaping-associated lung injury can manifest as an acute eosinophilic pneumonia-like pattern, presenting with rapidly progressive respiratory failure and a CT pattern that mimics non-cardiogenic pulmonary edema. Recognizing this presentation is crucial because, like classic acute eosinophilic pneumonia, patients are highly responsive to prompt corticosteroid therapy and can be quickly extubated.

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