CTICasesDiffuse Large B-cell Lymphoma (Thoracic Manifestations)
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Imaging findings
Chest radiograph revealed a multilobulated, extra-pulmonary mass with sharp borders in the right apex and a chest wall defect. Lateral abnormality appearing extra-pulmonary, broad-based with a smooth medial margin, and a paraspinal bump were also noted. There was a visible difference in density in the soft tissues of the left chest wall and supraclavicular regions. PET/CT confirmed widespread lymphomatous involvement, including a large supraclavicular mass, large axillary and subpectoral masses, the right upper lobe mass with rib and chest wall involvement, axillary lymphadenopathy, and a paraspinal abnormality with associated bone involvement.
Key takeaways
This case provides a comprehensive illustration of the varied and extensive thoracic manifestations of Diffuse Large B-cell Lymphoma (DLBCL), demonstrating how a single malignancy can present with multiple extra-pulmonary masses, chest wall involvement, paraspinal lesions, and diffuse soft tissue infiltration, all visible across different imaging modalities.
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