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Septic Lakes in Interstitial Pulmonary Edema

Imaging findings

Chest radiograph shows extensive septal lines (Kerley B and C lines). Chest CT shows severe thickening of the interlobular septa containing oval-shaped or rounded fluid-filled spaces ('septal lakes') and peribronchial cuffing, which cleared completely following diuretic therapy.

Key takeaways

Septal lakes (historically termed lymphatic curls) represent focal accumulations of fluid within severely edematous interlobular septa. Radiographically, they can mimic pulmonary nodules or metastases, potentially leading to unnecessary biopsies. Dynamic clearance after diuresis confirms the diagnosis of pulmonary edema.

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