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Secondary Pulmonary Hemosiderosis from Mitral Stenosis

Imaging findings

CT chest in an 83-year-old female post-TMVR shows permanent, thickened interlobular septal lines and ground-glass opacities. Mitral valve replacement site shows hypokinesis of the anterior wall and diastolic septal bounce.

Key takeaways

Secondary pulmonary hemosiderosis is a chronic complication of long-standing mitral valve disease (regurgitation or stenosis) causing pulmonary venous hypertension. Chronic alveolar micro-hemorrhage leads to hemosiderin deposition in the interstitium, prompting progressive septal fibrosis and occasionally dystrophic pulmonary ossification (DPO).

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