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Benign Metastasizing Leiomyoma

Imaging findings

CT chest shows countless, tiny, stable random pulmonary nodules that have remained completely unchanged over 19 years in a patient who previously underwent a hysterectomy for uterine fibroids. Biopsy confirmed smooth muscle cells consistent with BML.

Key takeaways

Benign metastasizing leiomyoma (BML) is a rare condition in which histologically benign uterine leiomyomas metastasize to extra-uterine sites, most commonly the lungs. They typically present as multiple, well-circumscribed, slow-growing or stable nodules in premenopausal women, often showing no progression post-hysterectomy/menopause.

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