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Exogenous Lipoid Pneumonia

Imaging findings

CT chest in a patient post-COVID-19 infection shows severe, progressive, upper-lobe-predominant consolidations. Bronchoscopic biopsy demonstrated exogenous lipoid pneumonia, which cleared rapidly with steroids. The patient admitted to applying Vicks VapoRub extensively over his face and neck.

Key takeaways

Exogenous lipoid pneumonia is caused by the inhalation or aspiration of lipid-containing substances, such as mineral oils or petroleum jelly (like Vicks VapoRub). It classically manifests as low-attenuation (fat density) consolidations on CT, but can present as non-specific consolidation with rapid response to steroids once the exposure is discontinued.

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