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Airway-Centered EVALI

Imaging findings

CT chest in a 30-year-old male shows diffuse ground-glass opacities, sparing along the bronchovascular bundles, and poorly-defined centrilobular ground-glass nodules throughout both lungs. The patient has a history of heavy THC vaping, and COVID-19 testing was negative.

Key takeaways

EVALI can radiographically manifest as an airway-centered process. The presence of diffuse centrilobular nodules and sparing of the immediate peribronchovascular interstitium on CT represents an organizing pneumonia or acute bronchiolitis pattern triggered by toxic chemical inhalation, responding rapidly to steroids.

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