CTICasesCoumadin-Induced Tracheobronchial Calcification
Imaging findings
Chest radiograph demonstrates extensive, dense calcification of the cartilaginous rings of the trachea and proximal bronchi. A classic caged-ball prosthetic aortic valve (Star-Edwards valve) is also visible.
Key takeaways
Long-term warfarin (Coumadin) therapy can lead to extensive calcification of the tracheobronchial cartilages. Warfarin inhibits vitamin K, which is required for the activation of matrix Gla protein, a potent inhibitor of tissue calcification. When this protein is inactive, calcium precipitates into cartilaginous structures.
AI-assisted summary — may contain errors. Verify against the source video. Learn more
More from this webinar
- Uncorrected Ventricular Septal Defect with Bronchial Artery AneurysmCongenital
- Cavitating Pulmonary Rheumatoid NodulesAutoimmune
- Pericardial Epithelioid HemangioendotheliomaNeoplastic
- Anterior Mediastinal LymphangiomaCongenital
- Cor Triatriatum Dexter and SinisterCongenital
- Traumatic Myocardial ContusionTrauma
- Coarctation of the Aorta with Bicuspid Aortic ValveCongenital
- Granulomatosis with Polyangiitis (GPA)Autoimmune
See all cases from August 11, 2017 →