CTICasesGranulomatosis with Polyangiitis (GPA)
Imaging findings
Serial CT scans demonstrate a variety of findings including patchy consolidations, discrete nodules, and diffuse alveolar hemorrhage settling in the lung bases. Biopsy of the lung lesions showed organizing pneumonia. Striking clinical findings include severe necrotic skin lesions of the fingers and toes.
Key takeaways
Granulomatosis with polyangiitis (GPA) is a systemic small-to-medium vessel necrotizing vasculitis that can present with a wide variety of lung findings, including nodules, consolidation, organizing pneumonia, and diffuse alveolar hemorrhage. Extrapulmonary manifestations like severe cutaneous necrosis of the digits and glomerulonephritis are common.
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