CTICasesMediastinal inflammatory myofibroblastic tumor
Imaging findings
Chest CT in a 30-year-old female shows a well-defined, homogeneous, solid mass located in the right cardiophrenic fat space. Histopathological analysis following surgical resection confirmed an inflammatory myofibroblastic tumor with characteristic stromal spindle cell proliferation.
Key takeaways
Inflammatory myofibroblastic tumors are rare mesenchymal neoplasms that most commonly occur in the lungs but can arise in the mediastinum (such as the cardiophrenic angle). They are benign or low-grade malignant tumors that may show gene rearrangements (e.g., ALK) and are managed primarily with surgical resection.
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