CTICasesPulmonary plasmacytoma with localized amyloidosis
Imaging findings
Abdominal and chest CT show a small, focal nodular opacity in the right middle lobe alongside small, scattered pulmonary cysts, some containing internal tissue and septations. Biopsy of the nodule confirmed a clonal proliferation of lambda light-chain restricted plasma cells (plasmacytoma) and localized amyloidosis.
Key takeaways
Pulmonary plasmacytoma can occur as a localized lesion associated with extracellular light-chain protein deposition and localized amyloidosis. This clonal plasma cell proliferation can also lead to the development of pulmonary cysts, resembling findings in systemic amyloidosis or light chain deposition disease.
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