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Hodgkin Lymphoma with Tracheal Involvement

Imaging findings

CT shows a large lesion in the lower neck and upper mediastinum, extrinsic to the trachea, pushing on and narrowing the lumen with a smooth interface. A necrotic-looking mass is observed in the intermediastinum. The lesion appeared like a thyroid goiter on a radiograph.

Key takeaways

Hodgkin lymphoma can involve the trachea, typically through direct extension from adjacent lymph nodes, particularly in young patients. While primary tracheal tumors are often considered (e.g., adenoid cystic carcinoma, squamous cell carcinoma), lymphoma should be in the differential for extrinsic tracheal compression, especially with mediastinal masses.

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