CTICasesRespiratory Bronchiolitis
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Imaging findings
Chest CT in an active smoker demonstrates centrilobular emphysema and diffuse, poorly defined centrilobular ground glass nodules with a middle and upper-lung predominance, representing respiratory bronchiolitis.
Key takeaways
Respiratory bronchiolitis (RB) is a common, benign, smoking-related lung disease characterized radiographically by poorly defined, upper-lung predominant centrilobular ground glass nodules. It represents an inflammatory reaction of alveolar macrophages to cigarette smoke within the first- and second-order respiratory bronchioles, and can be seen in asymptomatic active smokers as well as those with respiratory bronchiolitis-interstitial lung disease (RB-ILD).
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