CTICasesDiffuse Alveolar Hemorrhage in Goodpasture Syndrome
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Imaging findings
High-resolution chest CT reveals extensive ground glass opacities with superimposed interlobular and intralobular septal thickening, creating a classic 'crazy-paving' pattern, as well as confluent areas of dependent airspace consolidation, typical of diffuse alveolar hemorrhage.
Key takeaways
Goodpasture syndrome is an autoimmune disease characterized by anti-glomerular basement membrane (anti-GBM) antibodies that can cause rapidly progressive glomerulonephritis and life-threatening diffuse alveolar hemorrhage. Radiographically, alveolar hemorrhage presents with ground glass opacities, crazy paving, and consolidation, often recurring in episodic flares.
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