Secondary Pericardial Lymphoma from Testicular Lymphoma
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Imaging findings
Initial staging CT demonstrates subtle nodularity and thickening of the pericardium. Follow-up CT and PET/CT imaging obtained a few months later show rapid progression into a hypermetabolic, infiltrative pericardial mass with associated soft tissue extending along the right atrioventricular groove, indicating secondary pericardial involvement by aggressive testicular lymphoma.
Key takeaways
Pericardial involvement by lymphoma is most frequently a secondary manifestation of systemic disease rather than a primary tumor. It may initially present with very subtle, easily overlooked pericardial thickening or fluid, which can rapidly progress to severe, infiltrative tumor infiltration mimicking other primary pericardial pathologies.
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