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Desquamative interstitial pneumonia (DIP) or amyloidosis

Imaging findings

CT scan over an 11-year period shows progression of lower lobe peribronchovascular cysts into confluent cystic spaces with mild traction bronchiectasis and surrounding ground-glass opacity in a former smoker.

Key takeaways

Desquamative interstitial pneumonia (DIP) can progress to end-stage fibrosis with cystic change despite smoking cessation. Differential diagnosis for basal predominant cysts with vessels running through their walls includes LIP, DIP, and amyloidosis.

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