CTICasesIPF progressing from recurrent organizing pneumonia to UIP
Imaging findings
Serial CT scans over a 12-year period track the progression from an initial organizing pneumonia/DAD pattern to recurrent patchy ground-glass and bronchocentric opacities, and finally to end-stage pulmonary fibrosis with classic honeycombing and traction bronchiectasis (UIP pattern) requiring lung transplantation.
Key takeaways
Idiopathic pulmonary fibrosis (IPF/UIP) can be the end-stage pathway of recurrent acute or subacute lung injuries (such as organizing pneumonia and DAD) rather than a slowly progressive primary process from onset.
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